Show patients their result before they treat.
A polynucleotide 'salmon DNA' injectable popular in Korea for repairing skin from within.
Sarah Jenkins
Plan • Injectable
Recommended Protocol
Rejuran
Polynucleotide skin healing injectable
Maintenance & Follow-Up
Ongoing plan
Rejuran is a South Korean polynucleotide injectable made from purified salmon DNA, microinjected to reduce inflammation, support skin repair, and improve elasticity and texture. It's a 'skin healing' treatment, not a filler. Rejuran is NOT FDA-approved in the United States.
Rejuran is PharmaResearch's polynucleotide (PN) injectable, derived from purified salmon DNA fragments. Hugely popular in South Korea, it's microinjected into the skin to reduce inflammation, support repair, improve elasticity and texture, and strengthen the skin barrier — a 'skin healing' rather than a volumizing treatment. Variants target the face, under-eyes, and overall skin quality. Rejuran is not currently FDA-approved in the United States.
For a practice, Rejuran represents the fast-rising polynucleotide trend that patients increasingly ask about by name. Addressing it honestly — its regenerative mechanism, its non-approved US status, and FDA-cleared adjacent options like microneedling with growth factors or exosome-supported protocols — builds authority. Previewing improved skin texture and tone on the patient's own photo keeps the conversation grounded in achievable, compliant results.
Rejuran
Made by
PharmaResearch (South Korea)
Category
Polynucleotide skin healing injectable
Type
Injectable / medical supply
US regulatory status
Not FDA-approved in the US; widely used in South Korea and internationally for skin healing.
See the full treatment category — what it does, the concerns it solves, and how it fits into a visual 12-month plan.
Each concern maps to its full range of options — and lets patients preview their result before they commit.
Small, shallow wrinkles that show up first around the eyes, mouth, and forehead.
Explore concernSmoothing rough, uneven, or bumpy facial skin for a refined, radiant complexion.
Explore concernPatchy discoloration, blotchiness, and dark spots that leave the complexion looking uneven and lacking clarity.
Explore concernA tired, lackluster complexion lacking radiance from dehydration, dead-skin buildup, and environmental stress.
Explore concernPits, raised marks, and discoloration left behind after breakouts heal.
Explore concernBrightening dark circles, shadows, and hollows that make the under-eye look tired.
Explore concernThin, finely wrinkled skin resembling crepe paper, common on the under-eyes, neck, arms, and décolletage.
Explore concernCommon questions patients ask about Rejuran — and what practices should be ready to answer.
No. Rejuran is not currently FDA-approved in the United States, though it's widely used in South Korea and internationally. Patients should confirm what regenerative options are FDA-cleared in the US.
Polynucleotides derived from purified salmon DNA fragments, which support skin repair and reduce inflammation when microinjected.
It's used to improve skin texture, elasticity, fine lines, and under-eye quality, and to strengthen the skin barrier — it heals skin rather than adding volume.
Patients weigh their options by name. Browse the alternatives Afters can visualize and plan.
Afters simulates the outcome on a patient's own photo and builds a visual 12-month plan — so consults convert and average ticket climbs.